Dermatitis, Irritant Contact

What is occupational irritant contact dermatitis?

• context Dermatitis is a localized inflammation of the skin. In general, inflammation refers to a condition in the body when it is trying to react to a localized injury of tissues. Signs of inflammation include some or all of the following: redness, heat, swelling, pain.
• context Occupational irritant contact dermatitis is an inflammation caused by substances found in the workplace that come in direct contact with the skin. Signs of irritant contact dermatitis include redness of the skin, blisters, scales or crusts. These symptoms do not necessarily occur at the same time or in all cases. This kind of dermatitis is caused by chemicals that are irritating (e.g., acids, bases, fat-dissolving solvents) to the skin and is localized to the area of contact.
• context Another kind of contact dermatitis, allergic contact dermatitis, is different because it is an allergic response to skin contact with some allergy-causing material (e.g., poison ivy). Another difference is that allergic dermatitis can occur in other places on the body that did not come in contact with the allergy-causing material.

How does irritant contact dermatitis develop?

• context In the workplace, irritant contact dermatitis can develop after a short, heavy exposure or a repeated or prolonged, low exposure to a substance. The appearance of irritant contact dermatitis varies considerably according to the conditions of exposure. For example, an accidental contact with a strong irritant causes immediate blisters. Contact with a mild irritant may only produce redness of the skin. However, if the irritation continues, small lesions or sores appear on the reddened area; afterwards crusts and scales form. The skin damage usually heals a few weeks after exposure ends if no complications have arisen (e.g., no infections occurred).
• context The irritant action of a substance depends on its ability to change some properties of the outer layer of the skin that acts as a protective barrier against toxic substances. Among other changes, some substances can remove skin oils and moisture from the outer layer of the skin. This reduces the protective action of the skin and increases the ability of irritants to enter or infiltrate the skin. The removal of fat or fat-like material from the skin is also responsible for the dryness, cracking and whitening of the skin.
• context To produce the damage, the irritant substance must infiltrate the outer layer of the skin. Following infiltration, the substance comes into contact with cells and tissues. The substance also reacts with certain chemicals naturally present (endogenous) in cells and tissues. These reactions produce skin damage. The body's first reaction to the damage is a localized acute inflammation. The cells and tissues try to repair the damage and set up a defensive response to remove the invading material causing the damage. During the body's defensive response phase, a person may experience pain, warmth, redness and swelling in the irritated area.
• context Minimal skin damage, as in the thickening of the inner layer of the skin, will not be visible. However, when the damage is severe, the skin shows signs of chapping, scaling, and blistering. Some skin cells also die. Typically, an irritant reaction develops within a few hours from exposure and is at its worst after approximately twenty-four hours.

What are factors contributing to irritant contact dermatitis?

Factors contributing to irritation include Factors peculiar to individual workers are also important. Hereditary factors influence the variety of reactions seen in different persons when exposed to the same irritant. The part of the body that comes in contact with an irritant substance is another factor to remember. The penetration of substances varies over different body regions. For example, some substances penetrate the face and the upper back more quickly than the arms. Environmental factors play a significant role. For example, hot, humid workplaces cause workers to sweat. Sweat can dissolve some types of industrial chemical powders that may come in contact with the skin. This increases their toxic or irritant effects of the chemicals because solutions penetrate the skin more readily than solids. On the other hand, sweating may also have a protective function because it may dilute or wash out substances. Working where the air humidity is low or where the skin is wet for prolonged and repeated periods can cause chapping of the skin that, in turn, can increase the possibility of irritation. Friction against the skin, occurring while operating grinding machines and other equipment can scrape away the skin, reducing its protective action against irritants. Clothing soaked with irritants is another important factor. Cuts or skin injuries enable irritant substances to penetrate the skin more readily. Table 1 summarizes some factors that contribute to skin irritation.

• context the chemical properties of the substance (for example, is it an acid, an alkali, or a salt),
• context the amount and concentration of chemical coming in contact with the skin, and
• context the length and frequency of the exposure.

What occupations are at risk?

Table 2 lists some occupations where irritant contact dermatitis has been seen. Table 2 also gives examples of workplace chemicals that can cause irritant contact dermatitis; however, this list is not intended to be comprehensive. New materials and processes can present workers with chemical exposures and risks that they have not experienced previously.

• context Condition | Irritant
• context Agriculture workers | Artificial fertilizers, disinfectants, pesticides, cleaners, gasoline, diesel oil, plants and grains
• context Artists | Solvents, clay, plaster
• context Automobile and aircraft industry workers | Solvents, cutting oils, paints, hand cleansers
• context Bakers and confectioners | Flour, detergents
• context Bartenders | Detergents, wet work
• context Bookbinders | Solvents, glues
• context Butchers | Detergents, meat, waste
• context Cabinet makers, and carpenters | Glues, detergents, thinners, solvents, wood preservatives
• context Cleaners | Detergents, solvents, wet work
• context Coal miners | Dust (coal, stone), wet conditions
• context Construction workers | Cement
• context Cooks and caterers | Detergents, vegetable juices, wet work
• context Dentists and dental technicians | Detergents, hand cleansers, wet work
• context Dry cleaners | Solvents
• context Electricians | Soldering fluxes
• context Electroplaters | Acids, alkalis
• context Floor-layers | Solvents
• context Florists and gardeners | Manure, artificial fertilizers, pesticides, wet work
• context Hairdressers | Permanent wave solutions, shampoos, bleaching agents, wet work
• context Hospital workers | Detergents, disinfectants, foods, wet work
• context Homemakers | Detergents, cleansers, foods, wet work
• context Jewellers | Detergents, solvents
• context Mechanics | Oils, greases, gasoline, diesel fuel, cleaners, solvents
• context Metal workers | Cutting oils, solvents, hand cleansers
• context Nurses | Disinfectants, detergents, wet work
• context Office workers | Solvents, (photocopiers, adhesives)
• context Painters | Solvents, thinners, wallpaper adhesives, hand cleansers
• context Photography industry workers | Solvents, wet work
• context Plastics workers | Solvents, acids, styrene, oxidizing agents
• context Printers | Solvents
• context Rubber workers | Solvents, talc, zinc stearate, uncured rubber
• context Shoemakers | Solvents
• context Tannery workers | Acids, alkalis, reducing and oxidizing agents, wet work
• context Textile workers | Fibres, bleaching agents, solvents
• context Veterinarians and slaughterhouse workers | Disinfectants, wet work, animal entrails and secretions

How is it recognized?

• context Victims of irritant contact dermatitis often consult a doctor or nurse. While some experimental tests can provide an indication of the irritant potential of substances, no single test can reliably identify irritants in specific cases. In the evaluation of occupational irritant contact dermatitis, the best approach is to identify the conditions of exposure by discussing the victim's employment. The information to be gathered includes a detailed list of all chemicals in the individual's working environment; a detailed description of all processes involved in a day's work; and any information about other workers, if any, who have similar skin problems.

How is it treated?

• context Contact dermatitis may be treated with compresses, creams, ointments and skin cleansers. In general, people should protect their skin from physical trauma, chemical irritation, excessive sunlight, wind, and rapid temperature changes while the dermatitis is active.

How common is it?

• context The number of cases of irritant contact dermatitis in Canada at this time is not known. In Ontario, Canada, 1,000 compensation claims are reported for contact dermatitis each year. According to some US statistics, skin disorders comprise more than 35 percent of all occupationally related diseases. Among all occupational dermatitis, irritant contact dermatitis accounts for about 80 percent.